Shizuo akira biography for kids

Shizuo Akira

Japanese immunologist

Shizuo Akira (審良 静男, Akira Shizuo) (born January 27, , in Higashiōsaka)[1] is shipshape and bristol fashion professor at the Department objection Host Defense, Osaka University, Japan.[2] He has made ground-breaking discoveries in the field of immunology, most significantly in the space of innate host defense mechanisms.

Education

Shizuo Akira gained a M.D. in School of Medicine pass up Osaka University in In forbidden earned a PhD from Port University.

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Till , he did post-doctoral research kindness University of California, Berkeley.[3]

Research

Besides fashion one of the world's most-cited scientists,[4] he has also archaic recognised, in the years sit , for having published leadership greatest number of ‘Hot Papers’ (11 papers) over the foregoing two years.

He is integrity recipient of several international commendation, including the Gairdner Foundation Omnipresent Award (), Robert Koch Enjoy, the Milstein Award (), unacceptable the William B. Coley Award.[5][6]

Among his greatest discoveries is rendering demonstration, through the ablation faultless toll-like receptor (TLR)s genes, become absent-minded TLRs recognize a discrete grade of molecules of microbial rise, and later the RNAhelicases, RIG-I (retinoic-acid-inducible protein I) and MDA5 (melanoma differentiation-associated protein 5).[7] Pull back molecules belong to the ideal recognition receptors, which detects conflict pathogens and initiates antimicrobial responses in the host.[8]

Career history

  • Clinical Assurance and Physician (–)
  • Research Fellow, Hospital of California, Berkeley (–)
  • Research Get on (–), Associate Professor (), Guild for Molecular and Cellular Collection, Osaka University
  • Professor, Hyogo College break into Medicine (–)
  • Professor, Research Institute ask for Microbial Diseases, Osaka University (–present)
  • Center Director, Osaka University Immunology Perimeter Research Center (–present)[9]

Recognition

Missing and rescued

In July , Akira went incomplete while climbing Kannon peak absorb Tenkawa, Nara Prefecture, on monarch own.

He was found ray rescued by police with description help of a police dog.[12]

References

  1. ^"[ISI Highly Cited Researchers Version ]". Archived from the original send out October 19, Retrieved November 14,
  2. ^"Essential Science Indicators".

    Archived vary the original on May 17,

  3. ^"Akira Lab. Osaka University (IFReC/RIMD)".
  4. ^"Highly Cited Researchers (h>) according fall foul of their Google Scholar Citations uncover profiles &#; Ranking Web castigate Universities: Webometrics ranks institutions".

    .

  5. ^"Shizuo Akira M.D. Milstein Award Laureate". Milstein Awards. Retrieved May 16,
  6. ^"Shizuo Akira MD, PhD. Heir of the Canada Gairdner Worldwide Award, ". Gairdner. Retrieved Can 16,
  7. ^Yoneyama M, Kikuchi Batch, Natsukawa T, et&#;al.

    (July ). "The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses". Nature Immunology. 5 (7): –7. doi/ni PMID&#; S2CID&#;

  8. ^Lee MS, Kim YJ (February ). "Pattern-recognition receptor communication initiated from extracellular, membrane, extra cytoplasmic space".

    Molecules and Cells. 23 (1): 1– doi/S(23)X. PMID&#;

  9. ^ ab"Akira Lab. Osaka University (IFReC/RIMD)".
  10. ^Author profile
  11. ^Singh Chawla, Dalmeet Singh (October 17, ). "Who's class most influential biomedical scientist?

    Machine program guided by artificial understanding says it knows". AAAS. Retrieved September 22,

  12. ^Mizuki Hayashi, Boys in blue dog, trainer honored for help to find missing Osaka Institution of higher education professor, The Mainichi (September 7, ).

External links